Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Bioactive glass versus autologous platelet-rich fibrin for treating periodontal intrabony defects: A comparative clinical study


1 Department of Periodontology and Oral Implantology, Pandit Deendayal Upadhyay Dental College, Solapur, Maharashtra, India
2 Department of Periodontology and Oral Implantology, The Oxford Dental College, Bangalore, Karnataka, India

Correspondence Address:
Shravanthi Raghav Yajamanya,
Department of Periodontology and Oral Implantology, Pandit Deendayal Upadhyay Dental College, Kegaon, Solapur, Maharashtra
India
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Source of Support: None, Conflict of Interest: None

Background: To compare treatment modalities: Open flap debridement (OFD) alone (Group I), OFD in combination with PerioGlas® (Group II), and OFD in combination with autologous platelet-rich fibrin (PRF) (Group III) for periodontal intrabony defects (IBDs). Aim: To evaluate on clinical and radiographic basis, effectiveness of PerioGlas®, and PRF in treating IBDs. Settings and Design: IBDs selected on the basis of the inclusion criteria were randomly assigned to Groups I, II, and III by coin toss method. Materials and Methods: The study was conducted on patients reporting to the department of periodontology and oral implantology. Thirty-eight patients with ninety periodontal IBDs of moderate to severe periodontitis were selected and assigned to Groups I, II, and III. In each patient, a minimum number of two sextants were present with pocket depths ≥5 mm in at least three teeth. Statistical Analysis: Statistical analysis based on mean values, standard deviation, and P values. Results: Compared to baseline, 9 months postoperatively: (1) mean probing pocket depth reduction for Group I was 3.68 mm ± 0.72, for Group II was 5.57 mm ± 1.10, and for Group III was 6.11 mm ± 0.92. (2) The mean relative attachment level gain for Group I was 4.14 mm ± 0.76, for Group II was 6.57 mm ± 1.45, and for Group III was 6.74 mm ± 1.55. (3) Mean radiographic IBD fill for Group I was 69.29% mm ± 7.73, for Group II was 74.44% mm ± 8.57, and for Group III was 75.01% mm ± 7.85. Conclusion: This study shows marked improvements in the clinical parameters and radiographic outcomes with both PerioGlas® and autologous PRF to treat periodontal IBDs as compared to OFD alone.


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    -  Yajamanya SR
    -  Chatterjee A
    -  Hussain A
    -  Coutinho A
    -  Das S
    -  Subbaiah S
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