| ORIGINAL ARTICLE |
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| Year : 2013 | Volume
: 17
| Issue : 3 | Page : 338-344 |
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Periodontitis, diabetes mellitus, and the lopsided redox balance: A unifying axis
Gowri Pendyala1, Biju Thomas2, Saurabh Joshi3
1 Department of Periodontics, Rural Dental College, Loni, India
2 Department of Periodontics, A.B. Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India
3 Department of Pedodontics, Rural Dental College, Loni, Taluka Rahata, Ahmednagar, Maharashtra, India
Correspondence Address:
Gowri Pendyala
Department of Periodontics, Rural Dental College, Loni, Maharashtra
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-124X.115661
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Aim:The aim of present study was to evaluate and compare the total antioxidant capacity in the saliva of type 2 diabetes mellitus (DM) patients and healthy subjects, with and without periodontal disease. Materials and Methods: The study was designed as a case-control study, comprising of 120 male subjects, who were divided into four groups of 30 patients each. Group I: Thirty type 2 diabetic males with periodontal disease; Group II: Thirty type 2 diabetic males without periodontal disease; Group III: Thirty healthy males with periodontal disease; Group IV: Thirty healthy males without periodontal disease. After clinical measurement and sampling, the total antioxidant capacities in the saliva of type 2 diabetic and healthy men were determined, and the data were tested by non-parametric tests. The total antioxidant capacity of the clinical samples was determined spectrophotometrically. Results: The total antioxidant capacity in the saliva was the lowest in type 2 diabetic males with periodontal disease. The results were statistically significant. Conclusion: The findings of our study finally conclude that the salivary total antioxidant capacity is affected in type 2 diabetic males, in addition to the impact of periodontal disease, and hence, can be used as a useful marker of periodontitis in healthy and diabetic patients. |
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