Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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CASE REPORT
Year : 2014  |  Volume : 18  |  Issue : 6  |  Page : 789-793

Clinical and radiographic evaluation of recombinant human platelet derived growth factor with beta tricalcium phosphate in the treatment of a periodontal intrabony defect


Department of Periodontics and Oral Implantology, Gitam Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India

Correspondence Address:
Sneha Maroo
D/O Sanjay Maroo, Flat No. 402, Roshan Towers, Balajinagar, Siripuram, Visakhapatnam 530 003, Andhra Pradesh
India
Sneha Maroo
D/O Sanjay Maroo, Flat No. 402, Roshan Towers, Balajinagar, Siripuram, Visakhapatnam 530 003, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-124X.147441

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The need to increase the predictability of successful periodontal regeneration has led to the use of cell-stimulating proteins in combination with osteoconductive scaffolds and cells based on the principles of tissue engineering. The present case report describes the treatment of an intrabony defect with recombinant human platelet derived growth factor (rhPDGF) + β-tricalcium phosphate (β-TCP). A 25-year-old patient presented with a probing pocket depth of 9 mm mesial to the left maxillary molar. The radiograph revealed an intrabony defect with a depth of 4.23 mm. The defect was treated by open flap debridement and grafting with rhPDGF + β-TCP. On 9 months follow-up, the pocket depth reduced to 3 mm and the defect was completely filled as observed in radiographs and surgical re-entry. A gain in alveolar crest height was also observed.


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