Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2018  |  Volume : 22  |  Issue : 3  |  Page : 263-265

Grinspan syndrome with periodontitis: Coincidence or correlation?

1 Department of Dentistry, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
2 Department of Periodontics and Community Dentistry, Dr. Ziauddin Ahmad Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Correspondence Address:
Dr Lata Goyal
Department of Dentistry, All India Institute of Medical Sciences, Rishikesh - 249 201, Uttrakhand
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jisp.jisp_142_18

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Grinspan syndrome is a syndromic complex which comprises a triad of hypertension, diabetes, and oral lichen planus. It remains an enigmatic condition that whether it is separate entity or drug-induced lichenoid reaction emerging due to medications used to treat hypertension and diabetes. Diabetes is related to long-term hyperglycinemia leading to accelerated destruction of both nonmineralized connective tissue and bone leading to periodontitis. Moreover, there is also a possible link between cardiovascular disease and periodontitis. Here, we are presenting a case with the symptomatic triad fulfilling the diagnostic criteria of Grinspan syndrome. A 50-year-old female with type 2 diabetes mellitus and vascular hypertension came with the chief complaint of bleeding gums and severe burning sensation of the oral cavity. In addition, she was having generalized alveolar bone loss and clinical attachment loss. To the best of our knowledge, this coexistence has not been reported earlier. This needs further evaluation so that the preventive measures can be taken at early stage.

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