Journal of Indian Society of Periodontology
Journal of Indian Society of Periodontology
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Year : 2021  |  Volume : 25  |  Issue : 1  |  Page : 83-85

Proposal of a minimally invasive approach diagnosing desquamative gingivitis-associated diseases

1 Department of Dentistry, Montes Claros State University, Montes Claros, MG, Brazil
2 Department of Dentistry, Amazonas State University, Manaus, AM, Brazil

Correspondence Address:
Marco Túllio Brazao-Silva
Centro De Ciências Biológicas E Da Saúde - Faculdade De Odontologia (Prédio 6). Av. Rui Barbosa, No. 126, Bairro Vila Mauriceia, CEP 39401-088, Montes Claros, MG
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jisp.jisp_68_20

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Background: We aimed to present a minimally invasive clinical approach to collect a suitable sample for the laboratory diagnosis of desquamative gingivitis. Materials and Methods: The proposed technique involves Nikolsky's test for the collection of tissue samples. It consists of the histopathological analysis of the bullous membrane formed in cases with positive Nikolsky's sign (NS). Three patients without a previous diagnosis of the disease agreed to undergo this protocol before a biopsy. Results: The diagnoses of the three cases reported here were mucous pemphigoid (MP), pemphigus vulgaris (PV), and lichen planus (LP). The tissue samples collected using this technique were sufficient to microscopically observe partial-thickness epithelium (diagnosing PV) or full-thickness epithelium (diagnosing MP). The diagnosis of LP was only possible by conventional biopsy. Conclusion: We observed, for different cases, some advantages of the proposed technique: minimally invasive, potentially superior to exfoliative cytology, easily performed, and with low costs.

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