Effect of nano-crystalline silver membrane on early wound healing after periodontal surgery: A comparative randomized study

Kanika Aggarwal; Shipra Gupta; Shaveta Sood; Sonia Bhonchal Bhardwaj; Savita Prashar; Ashish Jain

doi:10.4103/jisp.jisp_17_21

Journal of Indian Society of Periodontology

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ORIGINAL ARTICLE

Year : 2021 | Volume : 25 | Issue : 6 | Page : 504-509

Effect of nano-crystalline silver membrane on early wound healing after periodontal surgery: A comparative randomized study

Kanika Aggarwal¹, Shipra Gupta², Shaveta Sood¹, Sonia Bhonchal Bhardwaj³, Savita Prashar⁴, Ashish Jain¹
¹ Department of Periodontology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India
² Unit of Periodontics, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India
³ Department of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India
⁴ Department of Biochemistry, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh, India

Correspondence Address:
Ashish Jain
Professor and Head, Department of Periodontology, Dr. Harvansh Singh Judge Institute of Dental Sciences and Hospital, Sector 25, Panjab University, Chandigarh
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/jisp.jisp_17_21

Background: Periodontal dressings are used for wound protection and patient comfort. Nano-silver particles have the ability to promote wound healing through anti-inflammatory properties. Hence, the present study aims to evaluate early wound healing parameters following periodontal surgery using nano-crystalline silver membrane as periodontal dressing. Materials and Methods: Forty-two systemically healthy patients diagnosed with chronic periodontitis indicated for periodontal flap surgery were enrolled for the present study. Post surgery, the patients were randomly allocated to either a nano-crystalline silver dressing (Acticoat^™) group (test group) or only the noneugenol dressing group (control group). Plaque index (PI) and wound healing index were recorded at the 7^th- and 14^th-day postsurgery. The microbiological analysis and vascular endothelial growth factor (VEGF) levels were evaluated at baseline and 7^th-day postsurgery. Results: The healing index was significantly higher in the test group as compared to the control group at days 7 and 14 (P < 0.001; P < 0.001). The colony-forming units/ml count of bacteria were significantly reduced postsurgery in the test group (P = 0.019). VEGF levels increased significantly 7^th-day postsurgery in the test group (P = 0.001). There was no statistically significant difference in the PI on the 7^th-day postsurgery between the two groups (P = 0.173). Conclusion: The results of the study revealed that silver can be used as a potent periodontal dressing ingredient that can decrease the microbial colonization beneath the pack and promote faster healing postsurgery due to its antimicrobial activity.

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