Journal of Indian Society of Periodontology

SHORT COMMUNICATION
Year
: 2020  |  Volume : 24  |  Issue : 6  |  Page : 593--596

Galleria mellonella as an experimental model for studying periodontopathogens


Thaís Aguiar Santos, Liliana Scorzoni, Aline de Castro Santos, Juliana Campos Junqueira, Ana Lia Anbinder 
 Department of Bioscience and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos, SP, Brazil

Correspondence Address:
Dr. Ana Lia Anbinder
Av Engenheiro Francisco Jose Longo, 777, Jardim Sao Dimas, Sao Jose dos Campos, SP
Brazil

In the present study, Galleria mellonella was evaluated as a potential infection model for periodontal bacteria, more specifically, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans. All the bacteria evaluated were pathogenic to G. mellonella, causing their death in a concentration-dependent manner, and a decrease in their hemocyte count. Moreover, it was possible to recover the bacteria from the larvae hemolymph and determine the colony-forming units per larvae. G. mellonella is an effective model that may help to better understand the host-microbe interactions in periodontics.


How to cite this article:
Santos TA, Scorzoni L, Santos Ad, Junqueira JC, Anbinder AL. Galleria mellonella as an experimental model for studying periodontopathogens.J Indian Soc Periodontol 2020;24:593-596


How to cite this URL:
Santos TA, Scorzoni L, Santos Ad, Junqueira JC, Anbinder AL. Galleria mellonella as an experimental model for studying periodontopathogens. J Indian Soc Periodontol [serial online] 2020 [cited 2021 May 6 ];24:593-596
Available from: https://www.jisponline.com/article.asp?issn=0972-124X;year=2020;volume=24;issue=6;spage=593;epage=596;aulast=Santos;type=0