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ORIGINAL RESEARCH
Salivary pH: A diagnostic biomarker
Sharmila Baliga, Sangeeta Muglikar, Rahul Kale
July-August 2013, 17(4):461-465
DOI
:10.4103/0972-124X.118317
PMID
:24174725
Objectives:
Saliva contains a variety of host defense factors. It influences calculus formation and periodontal disease. Different studies have been done to find exact correlation of salivary biomarkers with periodontal disease. With a multitude of biomarkers and complexities in their determination, the salivary pH may be tried to be used as a quick chairside test. The aim of this study was to analyze the pH of saliva and determine its relevance to the severity of periodontal disease.
Study Design:
The study population consisted of 300 patients. They were divided into three groups of 100 patients each: Group A had clinically healthy gingiva, Group B who had generalized chronic gingivitis and Group C who had generalized chronic periodontitis. The randomized unstimulated saliva from each patient was collected and pH was tested. Data was analyzed statistically using analysis of variance technique.
Results:
The salivary pH was more alkaline for patients with generalized chronic gingivitis as compared with the control group (
P
= 0.001) whereas patients with generalized chronic periodontitis had more acidic pH as compared with the control group (
P
= 0.001).
Conclusion:
These results indicate a significant change in the pH depending on the severity of the periodontal condition. The salivary pH shows significant changes and thus relevance to the severity of periodontal disease. Salivary pH may thus be used as a quick chairside diagnostic biomarker.
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REVIEW ARTICLES
Punica granatum: A review on its potential role in treating periodontal disease
Divyashree Prasad, Ravi Kunnaiah
July-August 2014, 18(4):428-432
DOI
:10.4103/0972-124X.138678
PMID
:25210254
A wide variety of plants possess enormous treasure of medicinal value. Majority of these medicinal plants have been used to treat various systemic conditions successfully. Over the recent years, use of these medicinal plants has resurfaced to treat oral conditions. Among the oral conditions, periodontal disease remains one of the most common. Alternative and preventive options has become the need of the hour in order to overcome the adverse effects of the antimicrobial agents used in large as an adjunct to mainstream periodontal treatment.
Punica granatum
(Pomegranate) is one of the oldest edible fruit which has a long history as a medicinal fruit. This review is an attempt to highlight the potential of
Punica granatum
as a preventive and therapeutic aid to periodontal disease.
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ORIGINAL ARTICLES
Evaluation of
Calendula officinalis
as an anti-plaque and anti-gingivitis agent
Mayur Sudhakar Khairnar, Babita Pawar, Pramod Parashram Marawar, Ameet Mani
November-December 2013, 17(6):741-747
DOI
:10.4103/0972-124X.124491
PMID
:24554883
Background:
Calendula officinalis (C. officinalis
)
,
commonly known as pot marigold, is a medicinal herb with excellent antimicrobial, wound healing, and anti-inflammatory activity.
Aim:
To evaluate the efficacy of
C. officinalis
in reducing dental plaque and gingival inflammation.
Materials and Methods:
Two hundred and forty patients within the age group of 20-40 years were enrolled in this study with their informed consent. Patients having gingivitis (probing depth (PD) ≤3 mm), with a complaint of bleeding gums were included in this study. Patients with periodontitis PD ≥ 4 mm, desquamative gingivitis, acute necrotizing ulcerative gingivitis (ANUG), smokers under antibiotic coverage, and any other history of systemic diseases or conditions, including pregnancy, were excluded from the study. The subjects were randomly assigned into two groups - test group (
n
= 120) and control group (n = 120). All the test group patients were advised to dilute 2 ml of tincture of calendula with 6 ml of distilled water and rinse their mouths once in the morning and once in the evening for six months. Similarly, the control group patients were advised to use 8 ml distilled water (placebo) as control mouthwash and rinse mouth twice daily for six months. Clinical parameters like the plaque index (PI), gingival index (GI), sulcus bleeding index (SBI), and oral hygiene index-simplified (OHI-S) were recorded at baseline (first visit), third month (second visit), and sixth month (third visit) by the same operator, to rule out variable results. During the second visit, after recording the clinical parameters, each patient was subjected to undergo a thorough scaling procedure. Patients were instructed to carry out regular routine oral hygiene maintenance without any reinforcement in it.
Results:
In the absence of scaling (that is, between the first and second visit), the test group showed a statistically significant reduction in the scores of PI, GI, SBI (except OHI-S) (
P
< 0.05), whereas, the control group showed no reduction in scores when the baseline scores were compared with the third month scores. Also, when scaling was performed during the third month (second visit), there was statistically significant reduction in the scores of all parameters, when the third month scores were compared with the sixth month scores in both groups (
P
< 0.05), but the test group showed a significantly greater reduction in the PI, GI, SBI, and OHI-S scores compared to those of the control group.
Conclusion:
Within the limits of this study, it can be concluded that calendula mouthwash is effective in reducing dental plaque and gingivitis adjunctive to scaling.
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REVIEW ARTICLES
Antimicrobial photodynamic therapy: An overview
S Rajesh, Elizabeth Koshi, Koshi Philip, Aparna Mohan
October-December 2011, 15(4):323-327
DOI
:10.4103/0972-124X.92563
PMID
:22368354
Inflammatory periodontal disease caused by dental plaque is characterized by the clinical signs of inflammation and loss of periodontal tissue support. The mechanical removal of this biofilm and adjunctive use of antibacterial disinfectants and antibiotics have been the conventional methods of periodontal therapy. But the removal of plaque and the reduction in the number of infectious organisms can be impaired in sites with difficult access. The possibility of development of resistance to antibiotics by the target organism has led to the development of a new antimicrobial concept with fewer complications. Photodynamic therapy (PDT) involves the use of low power lasers with appropriate wavelength to kill micro organisms treated with a photosensitizer drug. PDT could be a useful adjunct to mechanical as well as antibiotics in eliminating periopathogenic bacteria.
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ORIGINAL ARTICLES
Estimation of nitric oxide as an inflammatory marker in periodontitis
KB Menaka, Amitha Ramesh, Biju Thomas, N Suchetha Kumari
May-August 2009, 13(2):75-78
DOI
:10.4103/0972-124X.55842
PMID
:20407654
Nitric oxide (NO) is not only important in host defense and homeostasis but it is also regarded as harmful and has been implicated in the pathogenesis of a wide variety of inflammatory and autoimmune diseases. The presence of NO in periodontal disease may reflect the participation of an additional mediator of bone resorption responsible for disease progression. The aim of this study was to assess the level of NO in serum in chronic periodontitis, and correlate these levels with the severity of periodontal disease. Sixty subjects participated in the study and were divided into two groups. NO levels were assayed by measuring the accumulation of stable oxidative metabolite, nitrite with Griess reaction. Results showed subjects with periodontitis had significantly high nitrite in serum than healthy subjects. NO production is increased in periodontal disease, this will enable us to understand its role in disease progression and selective inhibition of NO may be of therapeutic utility in limiting the progression of periodontitis.
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CASE REPORTS
Platelet-rich-fibrin: A novel root coverage approach
K Anilkumar, A Geetha, Umasudhakar , T Ramakrishnan, R Vijayalakshmi, E Pameela
January-April 2009, 13(1):50-54
DOI
:10.4103/0972-124X.51897
PMID
:20376243
Treatment of gingival recession has become an important therapeutic issue due to increasing cosmetic demand. Multiple surgical procedures have been developed to obtain predictable esthetic root coverage. More specifically, after periodontal regenerative surgery, the aim is to achieve complete wound healing and regeneration of the periodontal unit. A recent innovation in dentistry is the preparation and use of platelet-rich plasma (PRP), a concentrated suspension of the growth factors, found in platelets. These growth factors are involved in wound healing and postulated as promoters of tissue regeneration. This paper reports the use of PRF membrane for root coverage on the labial surfaces of the mandibular anterior teeth. This was accomplished using laterally displaced flap technique with platelet rich fibrin (PRF) membrane at the recipient site.
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ORIGINAL ARTICLES
Future impact of nanotechnology on medicine and dentistry
Mallanagouda Patil, Dhoom Singh Mehta, Sowjanya Guvva
May-August 2008, 12(2):34-40
DOI
:10.4103/0972-124X.44088
PMID
:20142942
The human characteristics of curiosity, wonder, and ingenuity are as old as mankind. People around the world have been harnessing their curiosity into inquiry and the process of scientific methodology. Recent years have witnessed an unprecedented growth in research in the area of nanoscience. There is increasing optimism that nanotechnology applied to medicine and dentistry will bring significant advances in the diagnosis, treatment, and prevention of disease. Growing interest in the future medical applications of nanotechnology is leading to the emergence of a new field called nanomedicine. Nanomedicine needs to overcome the challenges for its application, to improve the understanding of pathophysiologic basis of disease, bring more sophisticated diagnostic opportunities, and yield more effective therapies and preventive properties. When doctors gain access to medical robots, they will be able to quickly cure most known diseases that hobble and kill people today, to rapidly repair most physical injuries our bodies can suffer, and to vastly extend the human health span. Molecular technology is destined to become the core technology underlying all of 21
st
century medicine and dentistry. In this article, we have made an attempt to have an early glimpse on future impact of nanotechnology in medicine and dentistry.
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40
16,755
3,362
REVIEWS
Reactive oxygen species in periodontitis
Parveen Dahiya, Reet Kamal, Rajan Gupta, Rohit Bhardwaj, Karun Chaudhary, Simerpreet Kaur
July-August 2013, 17(4):411-416
DOI
:10.4103/0972-124X.118306
PMID
:24174716
Recent epidemiological studies reveal that more than two-third of the world's population suffers from one of the chronic forms of periodontal disease. The primary etiological agent of this inflammatory disease is a polymicrobial complex, predominantly Gram negative anaerobic or facultative bacteria within the sub-gingival biofilm. These bacterial species initiate the production of various cytokines such as interleukin-8 and TNF-α, further causing an increase in number and activity of polymorphonucleocytes (PMN) along with these cytokines, PMNs also produce reactive oxygen species (ROS) superoxide via the respiratory burst mechanism as the part of the defence response to infection. ROS just like the interleukins have deleterious effects on tissue cells when produced in excess. To counter the harmful effects of ROS, human body has its own defence mechanisms to eliminate them as soon as they are formed. The aim of this review is to focus on the role of different free radicals, ROS, and antioxidants in the pathophysiology of periodontal tissue destruction.
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SHORT COMMUNICATIONS
Use of collagen as a biomaterial: An update
Ruby Khan, Mohd Haroon Khan
July-August 2013, 17(4):539-542
DOI
:10.4103/0972-124X.118333
PMID
:24174741
Biomaterial science is an expanding area, which encompasses a wide range of medical knowledge involving arthroplasty, cochlear implants, heart valves designing, lenses, dental fixation and tissue engineering. Within this context,
in vitro
cell culture on polymer scaffolds is one of the adopted strategies for tissue creation. It consists of a specific cell line that is seeded onto a particular substrate. This scaffold should provide excellent biocompatibility, controllable biodegradability, appropriate mechanical strength, flexibility as well as the ability to absorb body fluids for delivery of nutrients. Collagen certainly fulfils these demands; therefore, it is often chosen as a biomaterial. Moreover, this protein is abundant in the animal kingdom and plays a vital role in biological functions, such as tissue formation, cell attachment and proliferation.
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REVIEWS
Biofilm and dental implant: The microbial link
Sangeeta Dhir
January-February 2013, 17(1):5-11
DOI
:10.4103/0972-124X.107466
PMID
:23633764
Mouth provides a congenial environment for the growth of the microorganisms as compared to any other part of the human body by exhibiting an ideal nonshedding surface. Dental plaque happens to be a diverse community of the microorganisms found on the tooth surface. Periodontal disease and the peri-implant disease are specific infections that are originating from these resident microbial species when the balance between the host and the microbial pathogenicity gets disrupted. This review discusses the biofilms in relation to the peri-implant region, factors affecting its presence, and the associated treatment to manage this complex microbial colony. Search Methodology: Electronic search of the medline was done with the search words: Implants and biofilms/dental biofilm formation/microbiology at implant abutment interface/surface free energy/roughness and implant, periimplantitis/local drug delivery and dental implant. Hand search across the journals - clinical oral implant research, implant dentistry, journal of dental research, international journal of oral implantology, journal of prosthetic dentistry, perioodntology 2000, journal of periodontology were performed. The articles included in the review comprised of
in vivo
studies,
in vivo
(animal and human) studies, abstracts, review articles.
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SHORT COMMUNICATION
Nicotine and periodontal tissues
Ranjan Malhotra, Anoop Kapoor, Vishakha Grover, Sumit Kaushal
January-March 2010, 14(1):72-79
DOI
:10.4103/0972-124X.65442
PMID
:20922084
Tobacco use has been recognized to be a significant risk factor for the development and progression of periodontal disease. Its use is associated with increased pocket depths, loss of periodontal attachment, alveolar bone and a higher rate of tooth loss. Nicotine, a major component and most pharmacologically active agent in tobacco is likely to be a significant contributing factor for the exacerbation of periodontal diseases. Available literature suggests that nicotine affects gingival blood flow, cytokine production, neutrophil and other immune cell function; connective tissue turnover, which can be the possible mechanisms responsible for overall effects of tobacco on periodontal tissues. Inclusion of tobacco cessation as a part of periodontal therapy encourages dental professionals to become more active in tobacco cessation counseling. This will have far reaching positive effects on our patients' oral and general health.
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REVIEW ARTICLE
Periodontitis and systemic diseases: A literature review
Abiodun O Arigbede, B Osagbemiro Babatope, M Kolude Bamidele
October-December 2012, 16(4):487-491
DOI
:10.4103/0972-124X.106878
PMID
:23493942
Studies have revealed possible link between periodontitis and different systemic diseases. There is need to review this interesting subject. The aims are: to provide a comprehensive literature that can easily be consulted, on the subject; to draw the attention of health practitioners to the impact of oral health on the general well-being; and to emphasize the need for a deeper interaction between medical and dental training. The Medline database was searched for relevant literature by combining each of the following terms, "oral health," "oral infection," "periodontitis," with "systemic diseases." Manual library search and review of bibliographies of published literature were also conducted. Periodontitis is a constant potential source of infection and has been considered as a separate risk factor for some cardiovascular, respiratory, endocrine, musculoskeletal, and reproductive system related abnormalities. Oral health impacts on the general well-being, and if comprehensive health care is ever to be achieved, oral health should not be seen as a separate, distant, and less important area of health, which is totally unrelated to lifespan and its quality.
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PRIZE WINNING ESSAYS
Biofilms: A microbial home
Rita Chandki, Priyank Banthia, Ruchi Banthia
April-June 2011, 15(2):111-114
DOI
:10.4103/0972-124X.84377
PMID
:21976832
Microbial biofilms are mainly implicated in etiopathogenesis of caries and periodontal disease. Owing to its properties, these pose great challenges. Continuous and regular disruption of these biofilms is imperative for prevention and management of oral diseases. This essay provides a detailed insight into properties, mechanisms of etiopathogenesis, detection and removal of these microbial biofilms.
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ORIGINAL ARTICLES
Effect of retraction materials on gingival health: A histopathological study
Sushma Phatale, PP Marawar, Girish Byakod, Sanjay B Lagdive, Jitendra V Kalburge
January-March 2010, 14(1):35-39
DOI
:10.4103/0972-124X.65436
PMID
:20922077
Background:
Gingival retraction methods are used in dentistry for impressions of subgingival crown margins, such as, mechanical, chemical, chemicomechanical, and surgical. These methods may injure the gingival sulcular epithelium. Hence, the present study is carried out to evaluate the effect of different retraction materials, such as, Expasyl, Magic Foam Cord, and impregnated retraction cord on the gingival sulcular epithelium.
Materials and Methods:
This study included 30 cases of bilateral premolar extraction patients with Loe and Silness gingival index zero. Retraction materials were kept in the dry, isolated labial gingival sulcus for the required time. The retraction materials were removed by rinsing with water. Retracted gingiva of 2 - 3 mm from the gingival margin along with the tooth was extracted and the decalcified sections were microscopically studied.
Data analysis:
Data were analyzed by applying the chi-square test.
Results:
This study showed better results with retraction paste as compared to the retraction cord, and there was a significant association between retraction materials and the relative degree of injury to the sulcular epithelium.
Conclusion:
There is a significant association between retraction materials and gingival sulcular epithelium. It can be stated that impregnated retraction cord, may be used commonly but it needs proper tissue manipulation and is technique sensitive. Newly advanced material in the form of retraction paste like Expasyl or Magic Foam Cord was found to be better than cord as assessed histologically, it respects periodontium.
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26
9,626
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REVIEW ARTICLES
Prevalence of periodontitis in the Indian population: A literature review
Jacob P Shaju, RM Zade, Manas Das
January-March 2011, 15(1):29-34
DOI
:10.4103/0972-124X.82261
PMID
:21772718
Background:
Periodontitis is one of the major reasons for tooth loss in adults. India, with a population of over 1 billion, is bound to become a developed nation soon. This transition will require a population that is healthy, including in terms of periodontal health. Early studies done in India gave an indication that the population is highly susceptible to periodontitis.
Aim:
This paper reviews the prevalence of periodontitis in the Indian population.
Settings and Design:
Review of periodontitis prevalence studies on the Indian population.
Materials and Methods:
After identifying articles from PubMed and hand searching, the epidemiology of periodontitis is reviewed together with the case definition, study settings, type of population, age and other factors as all these are bound to affect the prevalence rates determined in various studies.
Statistical Analysis:
None.
Results:
This review identifies very limited number of studies that provide prevalence data and faces difficulty in comparing various studies due to nonstandardization of case definition and use of nonrepresentative samples. There is a high prevalence of periodontitis among the adults and the economically weak population.
Conclusions:
There is a very urgent need for standardized population-based studies with a robust design to identify the true prevalence of periodontitis, which in turn will help in planning oral health policies and creating the necessary infrastructure.
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ORIGINAL ARTICLES
Comparison of neutrophil functions in diabetic and healthy subjects with chronic generalized periodontitis
Neetha Shetty, Biju Thomas, Amita Ramesh
May-August 2008, 12(2):41-44
DOI
:10.4103/0972-124X.44089
PMID
:20142943
Background
: Diabetes mellitus is a systemic condition that has long been associated with an increased risk and severity of periodontal disease. Polymorphonuclear leukocytes (PMNs) play a key role in the maintenance of gingival and periodontal health. Reduced PMN function has been found in patients with diabetes.
Aim:
The objective of this study was to evaluate PMN functions in 15 diabetic patients with chronic generalized periodontitis.
Materials and Methods:
Chemotaxis, superoxide production, phagocytosis and killing of
Porphyromonas gingivalis
by diabetic PMNs were evaluated relative to healthy and matched controls.
Results:
These analyses revealed a significant (
P
< 0.01) depression in the number of diabetic PMNs migrating along an fMLP gradient. In addition, a significant (
P
< 0.01) enhancement of diabetic PMN superoxide production was observed. Phagocytosis (
P
< 0.05) and killing by diabetic PMN of
P. gingivalis
was also impaired significantly (
P
< 0.01).
[ABSTRACT]
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23
3,471
753
The challenge of antioxidants to free radicals in periodontitis
Gowri Pendyala, Biju Thomas, Suchetha Kumari
September-December 2008, 12(3):79-83
DOI
:10.4103/0972-124X.44100
PMID
:20142950
Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection. Patients with periodontal disease display increased PMN number and activity. This proliferation results in high degree of free radical release culminating in heightened oxidative damage to gingival tissues, periodontal ligament and alveolar bone. Damage mediated by free radicals can be mitigated by "ANTIOXIDANT DEFENSE SYSTEM ". Physiological alteration and pathological states produced by free radicals depend on disequilibrium between free radical production and antioxidant levels leading to oxidative stress. Hence this study has been designed to estimate the TOTAL ANTIOXIDANT CAPACITY in patients with PERIODONTITIS and healthy control subjects
[ABSTRACT]
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22
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Effect of periodontal therapy on hemoglobin and erythrocyte levels in chronic generalized periodontitis patients: An interventional study
Nupur Agarwal, Veerendra S.C. Kumar, Sheela A Gujjari
January-April 2009, 13(1):6-11
DOI
:10.4103/0972-124X.51887
PMID
:20376233
Aims and Objectives
: Anemia of chronic disease (ACD) is one of the most common forms of anemia. It is defined as anemia occurring in chronic infections, inflammatory conditions or neoplastic disorders which are not due to marrow deficiencies or other diseases, and occurring despite the presence of adequate iron stores and vitamins. Periodontitis is one of the most prevalent chronic inflammatory diseases in humans. This study aimed at finding out if periodontitis, like other inflammatory conditions, could lead to anemia.
Materials and Methods
: Thirty chronic generalized periodontitis male patients with hemoglobin levels below 15 mg/dl and serum ferritin values above 30 ng/ml were selected. The various blood parameters recorded at baseline were hemoglobin levels(Hb), erythrocyte count (RBC), erythrocyte sedimentation rate (ESR), mean corpuscular volume(MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). Periodontal parameters recorded at baseline included: plaque index, gingival index, probing pocket depth, clinical attachment level. Periodontal treatment including surgery if required was carried out in all the patients. Periodontal status of patients was monitored by repeating evaluation of periodontal indices at three months and at the end of one year. The hematological values were again measured at the end of one year.
Results:
The results showed that correction of periodontal inflammation resulted in a significant increase in hemoglobin levels and erythrocyte counts. The erythrocyte sedimentation rate showed a reduction indicating resolution of periodontal inflammation. There was a significant, but much lesser, improvement in MCV, MCH and MCHC values.
Conclusion:
The results of this study showed that treatment of periodontitis leads to an improvement in hematocrit and other related blood parameters in chronic generalized periodontitis patients with anemia. This provides evidence that periodontitis like other chronic diseases may also cause anemia.
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Evaluation of C-reactive protein and interleukin-6 in the peripheral blood of patients with chronic periodontitis
Dhruva Kumar Gani, Deepa Lakshmi, Rama Krishnan, Pamela Emmadi
May-August 2009, 13(2):69-74
DOI
:10.4103/0972-124X.55840
PMID
:20407653
Aims and Objectives:
The aim of the present study was to investigate systemic levels of inflammatory markers of cardiovascular diseases like C-reactive protein and interleukin-6 in patients with chronic periodontitis, in comparison to periodontally healthy individuals.
Materials and Methods:
A total of 42 individuals, both males and females above the age of 30 years, were included in the study. Healthy controls (Group I,
n
= 14), chronic localized periodontitis (Group II,
n
= 14), and chronic generalized periodontitis (Group III,
n
= 14), all without any medical disorder, were recruited. Peripheral blood samples were taken and C-reactive protein (CRP) levels were estimated in the serum samples by using the Particle-Enhanced Turbidimetric Immunoassay (PETIA) technique. Serum samples of Interleukin-6 (IL-6) were assayed by using the Chemiluminescent Immunoassay (IMMULITE) technique.
Results:
When mean CRP levels were compared between the groups, group III showed statistical significance when compared to group I (
P
= 0.04). Group III had a higher median IL-6 level (6.35 pg/mL) than Group II (< 5.0 pg/ mL) and group I (< 5.0 pg/mL). Differences in median values of IL-6 were not statistically significant in any group (
P
= 0.29).
Conclusion:
Periodontitis results in higher systemic levels of CRP and IL-6. These elevated inflammatory factors may increase inflammatory activity in atherosclerotic lesions and potentially increasing the risk for cardiovascular events.
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To evaluate the antigingivitis and antipalque effect of an
Azadirachta indica
(neem) mouthrinse on plaque induced gingivitis: A double-blind, randomized, controlled trial
Anirban Chatterjee, Mini Saluja, Nidhi Singh, Abhishek Kandwal
October-December 2011, 15(4):398-401
DOI
:10.4103/0972-124X.92578
PMID
:22368367
Background:
Azadirachta indica
(neem), a Meliaceae family tree, has been used in India for several decades for the treatment of several diseases in medicine and dentistry. Neem has been considered to have antiseptic activity, but still its use for the treatment of gingivitis and periodontitis is not very clear. Hence, the purpose of the present study was to assess the efficacy of neem based mouth rinse regarding its antigingivitis effect.
Materials and Methods:
Forty five subjects with plaque induced gingivitis were selected for the study. They were equally divided into three groups. Group I patients were asked to rinse with 15 ml of neem mouthwash twice daily, group II with 15 ml of chlorhexidine mouthwash twice daily, and group III with 15 ml of saline twice daily. The three groups were asked to perform the routine oral hygiene procedures thought out the study period. Bleeding on probing and gingivitis were evaluated by Muhlemann and Son's Sulcus bleeding index (1971) and Loe and Sillness gingival index (1963), respectively, at base line, after every week till one month.
Results:
Our result showed that an
A
.
indica
mouthrinse is equally effective in reducing periodontal indices as Chlorhexidine. The results demonstrated a significant reduction of gingival, bleeding, and plaque indices in both groups over a period of 21 days as compared to placebo.
Conclusion:
A
.
indica
-based mouth rinse is equally efficacious with fewer side effects as compared to chlorhexidine and may be used as an adjunct therapy in treating plaque induced gingivitis.
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Assessment of gingival thickness with regards to age, gender and arch location
Rajashri Kolte, Abhay Kolte, Aaditi Mahajan
July-August 2014, 18(4):478-481
DOI
:10.4103/0972-124X.138699
PMID
:25210263
Background:
There is a considerable intra and inter-individual variation in both width and thickness of the facial gingiva. As the attached gingiva is an important anatomic and functional landmark in the periodontium, the identification of gingival biotype is important in clinical practice since differences in gingival and osseous architecture have been shown to exhibit a significant impact on the outcome of restorative therapy. Hence, the aim of this study was to determine the variation in width and thickness of facial gingiva in the anterior segment with respect to age, gender and dental arch location.
Materials and Methods:
120 subjects were divided into three age groups: The younger age group (16-24 years), the middle age group (25-39 years) and the older age group (>40 years) with 20 males and 20 females in each group. The width of the gingiva was assessed by William's graduated probe and the thickness was determined using transgingival probing in the maxillary and mandibular anterior segment.
Results:
It was observed that the younger age group had significantly thicker gingiva but less width than that of the older age group. The gingiva was found to be thinner and with less width in females than males. The mandibular arch had thicker gingiva with less width compared to the maxillary arch.
Conclusion:
In the present study, we concluded that gingival thickness and width varies with age, gender and dental arch location.
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ORIGINAL RESEARCH
Indocyanine green-mediated photothermal therapy in treatment of chronic periodontitis: A clinico-microbiological study
Chetan Purushottam Raut, Kunal Sunder Sethi, Bhagyashree Rajendra Kohale, Alefiya Mamajiwala, Ayushya Warang
May-June 2018, 22(3):221-227
DOI
:10.4103/jisp.jisp_128_18
PMID
:29962701
Background:
Photodynamic therapy (PDT) has developed as an alternative treatment modality in periodontitis patients. Different photosensitizers used over the years have shown contradictory results. Thus, recently indocyanine green (ICG)-mediated photothermal therapy has emerged for the treatment of chronic periodontitis.
Aim:
The present study aimed at comparing and evaluating the effects of photothermal therapy using ICG in the treatment of chronic periodontitis with scaling and root planing (SRP).
Materials and Methods:
This was a randomized, controlled, clinical trial where fifty participants were equally divided into two groups, i.e., control group (SRP) and test group (SRP + photothermal therapy). Clinical parameters were evaluated at baseline and 6-month follow-up. These were plaque index (PI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL). Microbiological analysis of plaque sample was also done to check for anaerobic mixed flora.
Results:
Significant reduction was seen in PD, CAL, and BOP in the test group as compared to control group after 6 months (
P
< 0.05). However, intergroup comparison of PI showed nonsignificant results (
P
> 0.05). Anaerobic culture of plaque samples of test group also revealed a significant reduction of microorganisms in comparison with control group.
Conclusion:
ICG-mediated photothermal therapy can act as an alternative to antimicrobial PDT as an adjunct to SRP in the treatment of chronic periodontitis.
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19
4,179
549
POSITION UPDATE
An update on periodontic-orthodontic interrelationships
Aous Dannan
January-March 2010, 14(1):66-71
DOI
:10.4103/0972-124X.65445
PMID
:20922083
Talking about periodontic-orthodontic interrelationships is related primarily to the 1960s, where a generalized increase in salivary bacterial counts, especially Lactobacillus, had been shown after orthodontic band placement. The purpose of this article is to provide the dental practitioner with basic understanding of the interrelationship between periodontics and orthodontics by means of representing classical studies, and, to give an update on this topic by demonstrating the most recent opinions concerning periodontic-orthodontic interrelationships. Specific areas reviewed are the ability of orthodontic treatment to afford some degree of protection against periodontal breakdown, short-term and long-term effects of orthodontic treatment on the periodontium, and some mucogingival considerations. Topics considering orthodontic treatment in periodontally compromised patients were not included in this review. While past studies have shown that orthodontic treatment can positively affect the periodontal health, recent reviews indicate an absence of reliable evidence for the positive effects of orthodontic therapy on patients' periodontal status. Periodontic-orthodontic interrelationships are still controversial issues. However, a standard language between the periodontist and the orthodontist must always be established to eliminate the existing communications barrier, and to improve the outcomes of the whole treatment.
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ORIGINAL ARTICLES
Comparative evaluation of the antiplaque effectiveness of green tea catechin mouthwash with chlorhexidine gluconate
Harjit Kaur, Sanjeev Jain, Amritpal Kaur
March-April 2014, 18(2):178-182
DOI
:10.4103/0972-124X.131320
PMID
:24872625
An increasing number of people all around the world are turning to the nature by using the natural herbal products. Green tea with active chemical ingredients possesses diverse pharmacological properties.
Aim:
The aim of this study is to compare the antiplaque efficacy of green tea catechin mouthwash with chlorhexidine gluconate mouthwash.
Materials and Methods:
A single blinded cross-over study was conducted among 30 participants in the age group of 18-25 years. The mouthwash samples for the study were previously labeled assigning the letters: A (0.25% of green tea catechin mouthwash) and B (0.12% of chlorhexidine mouthwash). The study subjects were randomly divided into two groups of 15 each and the study was divided into two phases. In phase I, the mouthwash A was given to one group and other group was given mouthwash B. After a 15 day washout period, in phase II, both groups were given other mouthwash. At the end of each phase of 1 week, plaque score was recorded by using Turesky modification of the Quigley-Hein plaque index.
Results:
The plaque scores were compared and the difference between the green tea catechin and chlorhexidine mouthwash was determined by
t
-test. The difference between plaque scores were not statistically significant (
P
> 0.05). The results showed that both the groups that is green tea catechin mouthwash (0.25%) and chlorhexidine mouthwash (0.12%) have comparable results in plaque reduction.
Conclusion:
This study supports the effectiveness of green tea catechin mouthwash as an antiplaque agent. It should be explored as a cost-effective, long-term antiplaque rinse with prophylactic benefits.
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5,789
905
ORIGINAL RESEARCH
Comparative clinical evaluation of coronally advanced flap with or without platelet rich fibrin membrane in the treatment of isolated gingival recession
Murugan Thamaraiselvan, Sugumari Elavarasu, Suthanthiran Thangakumaran, Jayaprakash Sharanabasappa Gadagi, Thangavelu Arthie
January-February 2015, 19(1):66-71
DOI
:10.4103/0972-124X.145790
PMID
:25810596
Aim:
The aim of this study was to determine whether the addition of an autologous platelet rich fibrin (PRF) membrane to a coronally advanced flap (CAF) would improve the clinical outcome in terms of root coverage, in the treatment of isolated gingival recession.
Materials and
Methods:
Systemically healthy 20 subjects each with single Miller's class I or II buccal recession defect were randomly assigned to control (CAF) or test (CAF + PRF) group. Clinical outcome was determined by measuring the following clinical parameters such as recession depth (RD), recession width (RW), probing depth (PD), clinical attachment level (CAL), width of keratinized tissue (WKT), gingival thickness (GTH), plaque index (PI), and gingival index (GI) at baseline, 3
rd
, and 6
th
month postsurgery.
Results:
The root coverage was 65.00 44.47% in the control group and 74.16 28.98% in the test group at 6
th
month, with no statistically significant difference between them. Similarly, CAL, PD, and WKT between the groups were not statistically significant. Conversely, there was statistically significant increase in GTH in the test group.
Conclusion:
CAF is a predictable treatment for isolated Miller's class I and II recession defects. The addition of PRF to CAF provided no added advantage in terms of root coverage except for an increase in GTH.
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985
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© 2008 Journal of Indian Society of Periodontology | Published by Wolters Kluwer -
Medknow
Online since 1
st
November, 2008