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2013| November-December | Volume 17 | Issue 6
Online since
January 7, 2014
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ORIGINAL ARTICLES
Evaluation of
Calendula officinalis
as an anti-plaque and anti-gingivitis agent
Mayur Sudhakar Khairnar, Babita Pawar, Pramod Parashram Marawar, Ameet Mani
November-December 2013, 17(6):741-747
DOI
:10.4103/0972-124X.124491
PMID
:24554883
Background:
Calendula officinalis (C. officinalis
)
,
commonly known as pot marigold, is a medicinal herb with excellent antimicrobial, wound healing, and anti-inflammatory activity.
Aim:
To evaluate the efficacy of
C. officinalis
in reducing dental plaque and gingival inflammation.
Materials and Methods:
Two hundred and forty patients within the age group of 20-40 years were enrolled in this study with their informed consent. Patients having gingivitis (probing depth (PD) ≤3 mm), with a complaint of bleeding gums were included in this study. Patients with periodontitis PD ≥ 4 mm, desquamative gingivitis, acute necrotizing ulcerative gingivitis (ANUG), smokers under antibiotic coverage, and any other history of systemic diseases or conditions, including pregnancy, were excluded from the study. The subjects were randomly assigned into two groups - test group (
n
= 120) and control group (n = 120). All the test group patients were advised to dilute 2 ml of tincture of calendula with 6 ml of distilled water and rinse their mouths once in the morning and once in the evening for six months. Similarly, the control group patients were advised to use 8 ml distilled water (placebo) as control mouthwash and rinse mouth twice daily for six months. Clinical parameters like the plaque index (PI), gingival index (GI), sulcus bleeding index (SBI), and oral hygiene index-simplified (OHI-S) were recorded at baseline (first visit), third month (second visit), and sixth month (third visit) by the same operator, to rule out variable results. During the second visit, after recording the clinical parameters, each patient was subjected to undergo a thorough scaling procedure. Patients were instructed to carry out regular routine oral hygiene maintenance without any reinforcement in it.
Results:
In the absence of scaling (that is, between the first and second visit), the test group showed a statistically significant reduction in the scores of PI, GI, SBI (except OHI-S) (
P
< 0.05), whereas, the control group showed no reduction in scores when the baseline scores were compared with the third month scores. Also, when scaling was performed during the third month (second visit), there was statistically significant reduction in the scores of all parameters, when the third month scores were compared with the sixth month scores in both groups (
P
< 0.05), but the test group showed a significantly greater reduction in the PI, GI, SBI, and OHI-S scores compared to those of the control group.
Conclusion:
Within the limits of this study, it can be concluded that calendula mouthwash is effective in reducing dental plaque and gingivitis adjunctive to scaling.
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CASE REPORTS
Non-surgical treatment of peri-implantitis with the adjunctive use of an 810-nm diode laser
Marisa Roncati, Alessandra Lucchese, Francesco Carinci
November-December 2013, 17(6):812-815
DOI
:10.4103/0972-124X.124531
PMID
:24554897
An 810-nm diode laser was used to non-surgically treat a 7-mm pocket around an implant that had five threads of bone loss, BoP+, and exudate, and the patient was followed up for 5 years. Non-surgical treatment, home care reinforcement, clinical indices records, and radiographic examination were completed in two consecutive 1-h appointments within 24 h. The patient was monitored frequently for the first 3 months. Subsequently, maintenance debridement visits were scheduled at 3-month intervals. The patient had a decreased probing pocket depth and a negative BoP index compared to initial clinical data, and the results were stable after 1 year. After 5 years of follow-up visits, there appeared to be rebound of the bone level radiographically. Within the limits of this case report, conventional non-surgical periodontal therapy with the adjunctive use of an 810-nm diode laser may be a feasible alternative approach for the management of peri-implantitis. The 5-year clinical and radiographic outcomes indicated maintenance of the clinical improvement.
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9
REVIEW ARTICLES
Choice of diagnostic and therapeutic imaging in periodontics and implantology
Swarna Chakrapani, K Sirisha, Anumadi Srilalitha, Moogala Srinivas
November-December 2013, 17(6):711-718
DOI
:10.4103/0972-124X.124474
PMID
:24554878
Imaging forms an integral component for diagnosis of dental and in specific periodontal diseases. To date, intra-oral radiographic techniques are the main non-invasive diagnostic aids for the detection and assessment of internal changes in mineralized periodontal tissues like alveolar bone. These analog radiographic techniques suffer from inherent limitations like: Two dimensional projection, magnification, distortion, superimposition and misrepresentation of anatomic structures. The evolution of novel imaging modalities, namely cone beam computed tomography, tuned aperture CT empowered dental researchers to visualize the periodontium three dimensionally. This improves interpretation of structural and biophysical changes, ensures densitometric assessments of dentoalveolar structures including variations in alveolar bone density, and peri-implant bone healing more precisely. This detailed review, highlights current leading edge concepts, envisions a wide range of imaging modalities which pave the way for better understanding and early intervention of periodontal diseases.
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4
ORIGINAL ARTICLES
Bacteremia following scaling and root planing: A clinico-microbiological study
Alka S Waghmare, Priyanka B Vhanmane, B Savitha, Ruhee L Chawla, Hiroj S Bagde
November-December 2013, 17(6):725-730
DOI
:10.4103/0972-124X.124480
PMID
:24554880
Background:
Bacteremia frequently occurs after treatment procedures such as extractions, scaling, root planing, periodontal surgery. There is currently significant interest in the possibility that bacteremia with oral bacteria may play role in pathogenesis of atherosclerosis. There are well-conducted studies that have determined the frequency of passage of periodontal microorganisms to the bloodstream after periodontal treatment. There is scarce information related to the incidence of periodontopathic microorganisms during bacteremia induced by this procedure.
Aim:
The aim of this study was to establish the frequency of passage of periodontopathic microorganisms in peripheric blood after scaling and root planing in patients with periodontitis.
Materials and Methods:
Forty subjects with chronic periodontitis were included in the study. Blood samples were drawn from each patient at following intervals pre-treatment i.e., before SRP (P1), immediately after SRP (P2), and 30 minutes after SRP (P3). Following SRP, blood samples were analyzed for following microorganisms:
Porphyromonasgingivalis, Tannerella. forysthus, Eikenellanella. corrodens, Campylobacter species, Micromonas. micros,
and
Prevotella. intermedia
.
Statistical Analysis Used:
Chi-square test.
Results:
Bacteremia was found in 70% (28/40) immediately after SRP and after 30 min, it was reduced to 25% (10/40) and 7.5% (3/40) presented bacteremia before SRP.
Conclusions:
It was concluded that bacteremia frequently occurs immediately after SRP with
P. gingivalis
showing the highest frequency in blood.
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CASE REPORTS
Peripheral ossifying fibroma: A case report
Varshal J Barot, Sarath Chandran, Shivlal L Vishnoi
November-December 2013, 17(6):819-822
DOI
:10.4103/0972-124X.124533
PMID
:24554899
Localized gingival growths are one of the most frequently encountered lesions in the oral cavity, which are considered to be reactive rather than neoplastic. Different lesions with similar clinical presentation make it difficult to arrive at a correct diagnosis. These lesions include pyogenic granuloma, irritation fibroma, peripheral giant cell granuloma, peripheral ossifying fibroma (POF). Among these lesions, an infrequently occurring gingival lesion is the POF. Considerable confusion has prevailed in the nomenclature of POF due to its variable histopathologic features. This is a case presentation of a 30-year-old female with gingival overgrowth in the mandibular left canine-premolar region. Clinically, the lesion was asymptomatic, firm, pale pinkish and sessile. Surgical excision of the lesion was done followed by histopathologic confirmation with emphasis on the clinical aspect. Given the rate of recurrence for POF being 8-20%, close post-operative follow-up is required.
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3
Periodontal microsurgery: A case report
Janak Anil Kapadia, Surekha Y Bhedasgoankar, Saurabh Dilip Bhandari
November-December 2013, 17(6):790-792
DOI
:10.4103/0972-124X.124511
PMID
:24554892
The purpose of this article is to limelight the benefit of periodontal microsurgery in the surgical disciplines. It reviews the benefits and potential applications of magnification and microsurgery in the specialty of periodontics and a case report on microsurgical approach for free gingival graft surgery in the treatment of gingival recession. The increased demand for mucogingival esthetics has required the optimization of periodontal procedures. Microsurgery is a minimally invasive technique that is performed with the surgical microscope and adapted instruments and suture materials. Although this hardware and knowledge of various operations are necessary to achieve patient esthetic expectations, clinicians must be willing to undergo an extended period of systematic training to become familiar with novel operating procedures and instruments. This article describes the application of the surgical microscope to provide enhanced perioplastic treatment.
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Lateral sliding bridge flap technique along with platelet rich fibrin and guided tissue regeneration for root coverage
Kriti Agarwal, Chetan Chandra, Kanika Agarwal, Nishant Kumar
November-December 2013, 17(6):801-805
DOI
:10.4103/0972-124X.124525
PMID
:24554895
Gingival recession is defined as the apical migration of the gingival margin with exposure of root surfaces. The etiology of the condition is multifactorial. Given the high rate of gingival recession defects among the general population, it is imperative that dental practitioners have an understanding of the etiology, complications and management of the condition. A recent innovation in dentistry is the preparation and use of platelet-rich fibrin (PRF) for recession defects. The article presents a case report, which highlights the use of lateral sliding bridge flap along with PRF in a collagen membrane carrier (guided tissue regeneration) for the treatment of multiple recession defects.
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ORIGINAL ARTICLES
Prevalence of periodontitis among the adolescents aged 15-18 years in Mangalore City: An epidemiological and microbiological study
K Pallavi Nanaiah, DV Nagarathna, Nandini Manjunath
November-December 2013, 17(6):784-789
DOI
:10.4103/0972-124X.124507
PMID
:24554891
Background:
Periodontitis is a group of inflammatory diseases affecting the supporting tissues of the tooth. Both aggressive periodontitis (AP) and chronic periodontitis (CP) have a multifactorial etiology, with dental plaque as the initiating factor. However, the initiation and progression of periodontitis are influenced by other factors including microbiologic, social and behavioral and systemic and genetic factors. The prevalence of periodontal diseases varies in different regions of the world according to the definition of periodontitis and the study population, and there are indications that they may be more prevalent in developing than in developed countries.
Materials and Methods:
A cross-sectional study was conducted among the adolescents of 15-18 years of age in Mangalore City. One thousand one hundred students aged 15-18 years were selected for the study from the schools and colleges in Mangalore City using a convenient sampling method. The prevalence of AP and CP were assessed in the study using a community periodontal index. Students who were diagnosed clinically and radiographically were subjected to microbiological examination to confirm AP.
Results:
A high prevalence of gingivitis and periodontitis was found in students belonging to the lower socioeconomic status group compared with the higher socioeconomic groups, which were associated with poor oral hygiene habits. The prevalence of AP was found to be 0.36% and that of CP was found to be 1.5%.
Conclusion:
Oral diseases have a significant impact on the social and psychological aspects of an individual's life. Exposure to risk factors, such as age, low socio-economic status, poor education, low dental care utilization, poor oral hygiene levels, smoking, psychosocial stress and genetic factors are significantly associated with an increased risk of periodontitis among adolescents. Although genetic factors play a major role in periodontitis, the treatment outcome will still be influenced by environmental and behavioral factors.
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4
Light-cured resin "Barricaid" - An aesthetic and biocompatible dressing: A step ahead
Ellora Madan, Vipin Bharti, KK Chaubey, Vipin K. R. Arora, Rajesh K Thakur, Anubha Nirwal
November-December 2013, 17(6):753-756
DOI
:10.4103/0972-124X.124494
PMID
:24554885
Background:
Periodontal dressings have been used for several years as a protection over injured tissue to shield the area from further insult
.
Several dressings are commercially available. A recently introduced light-cured resin, claimed to be more biocompatible and esthetic, needs critical evaluation.
Aim:
To compare this dressing with most widely used non-eugenol pack in the perspective of esthetics, acceptance, and healing following periodontal flap surgery.
Materials and Methods:
Twenty patients suffering from generalized chronic periodontitis, requiring periodontal flap surgery on contralateral sides of the arch, were selected and divided randomly into Group I (control) and Group II (test). In Group I, a non-eugenol dressing and in Group II light-cured dressing were applied after flap surgery. Pain and discomfort scores were recorded on day 1, 2, and 3 while plaque scores, gingival index, and bleeding index were recorded on day 7. Patient's subjective evaluation and preference for the dressing material were recorded. The data was collected and statistically analyzed.
Results:
Group II showed better results than Group I when plaque scores, bleeding scores, modified gingival index scores, and pain and discomfort scores were compared though the differences were not statistically significant. Subjects found no unpleasant taste/smell and perceived the light-cured dressing to be better. A significantly higher number of patients preferred light-cured resin as a post-surgical dressing over Coe-pak.
Conclusion:
The light-cured dressing showed better patient acceptability and proves to be a better alternative to Coe-pak as a dressing material.
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4
A comparative evaluation of subepithelial connective tissue graft (SCTG) versus platelet concentrate graft (PCG) in the treatment of gingival recession using coronally advanced flap technique: A 12-month study
G. Naveen Vital Kumar, K. Raja Venkatesh Murthy
November-December 2013, 17(6):771-776
DOI
:10.4103/0972-124X.124502
PMID
:24554889
Objective:
The objective of this study was to clinically evaluate and compare the efficacy of platelet concentrate graft (PCG) with that of subepithelial connective tissue graft (SCTG) using a coronally advanced flap technique in the treatment of gingival recession.
Materials and Methods:
Twelve patients with a total of 24 gingival recession defects were selected and randomly assigned either to experimental site-A (SCTG) or experimental site-B (PCG). The clinical parameters were recorded at baseline up to 12 months post-operatively and compared.
Results:
The mean vertical recession depth (VRD) statistically significantly decreased from 2.50 ± 0.48 mm to 0.54 ± 0.50 mm with PCG and from 2.75 ± 0.58 mm to 0.54 ± 0.45 mm with SCTG at 12 months. No statistically significant differences between the treatments were found for VRD and clinical attachment level (CAL), while keratinized tissue width (KTW) gain was statistically significant.
Conclusion:
Both the SCTG and the PCG group resulted in a significant amount of root coverage. The PCG technique was less invasive and required minimal time and clinical maneuver. It resulted in superior aesthetic outcome and lower post-surgical discomfort at the 12 months follow-up.
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2
SHORT COMMUNICATION
Bdellovibrio bacteriovorus
: A future antimicrobial agent?
K Harini, Vidya Ajila, Shruthi Hegde
November-December 2013, 17(6):823-825
DOI
:10.4103/0972-124X.124534
PMID
:24554900
Bdellovibrio
and like organisms (BALOs) are small, predatory,
Deltaproteobacteria
that prey on other Gram-negative pathogens. Many authors have unfolded the possible use of BALOs as biological control agents in environmental as well as medical microbiological settings. They are found strongly associated with natural biofilms and recent studies have shown that effective predation occurs in these naturally occurring bacterial communities. Periodontal infections could also be an interesting target for the application of BALOs as biological Gram-negative bacteria and therefore potentially susceptible to BALOs antimicrobial agents. This proposition is based on the fact that almost all periodontal pathogens are predation. Accordingly, this review aims to present the evolution toward applying
Bdellovibrio bacteriovorus
as an antibacterial agent to deal with oral infections, general medical conditions, environmental and industrial issues.
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5
CASE REPORTS
Enamel pearl on an unusual location associated with localized periodontal disease: A clinical report
Shivani Sharma, Sumit Malhotra, Vidya Baliga, Manoj Hans
November-December 2013, 17(6):796-800
DOI
:10.4103/0972-124X.124520
PMID
:24554894
Bacterial plaque has been implicated as the primary etiologic factor in the initiation and progression of periodontal disease. Anatomic factors (such as enamel pearls) are often associated with advanced localized periodontal destruction. The phenomenon of ectopic development of enamel on the root surface, variedly referred to as enameloma, enamel pearl, enamel drop or enamel nodule, is not well-understood. Such an anomaly may facilitate the progression of periodontal breakdown. A rare case of enamel pearl on the lingual aspect of mandibular central incisor associated with localized periodontal disease is presented. Removal and treatment of enamel pearl along with possible mechanisms to account for the pathogenesis of ectopic enamel formation are also discussed.
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ORIGINAL ARTICLES
How to deal with morning bad breath: A randomized, crossover clinical trial
Jeronimo M Oliveira-Neto, Sandra Sato, Vinicius Pedrazzi
November-December 2013, 17(6):757-761
DOI
:10.4103/0972-124X.124497
PMID
:24554886
Context:
The absence of a protocol for the treatment of halitosis has led us to compare mouthrinses with mechanical oral hygiene procedures for treating morning breath by employing a hand-held sulfide monitor.
Aims:
To compare the efficacy of five modalities of treatment for controlling morning halitosis in subjects with no dental or periodontal disease.
Settings and Design:
This is a five-period, randomized, crossover clinical trial.
Materials and Methods:
Twenty volunteers were randomly assigned to the trial. Testing involved the use of a conventional tongue scraper, a tongue scraper joined to the back of a toothbrush's head, two mouthrinses (0.05% cetylpyridinium chloride and 0.12% chlorhexidine digluconate) and a soft-bristled toothbrush and fluoride toothpaste for practicing oral hygiene.
Statistical Analysis Used:
Data analysis was performed using SPSS version 17 for Windows and NCSS 2007 software (
P
< 0.05). The products and the periods were compared with each other using the Friedman's test. When significant differences (
P
< 0.05) were determined, the products and periods were compared in pairs by using the Wilcoxon's test and by adjusting the original significance level (0.05) for multiple comparisons by using the Bonferroni's method.
Results:
The toothbrush's tongue scraper was able to significantly reduce bad breath for up to 2 h. Chlorhexidine reduced bad breath only at the end of the second hour, an effect that lasted for 3 h.
Conclusions:
Mechanical tongue cleaning was able to immediately reduce bad breath for a short period, whereas chlorhexidine and mechanical oral hygiene reduced bad breath for longer periods, achieving the best results against morning breath.
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2
REVIEW ARTICLES
Poor periodontal health: A cancer risk?
KS Rajesh, Deepak Thomas, Shashikanth Hegde, M. S. Arun Kumar
November-December 2013, 17(6):706-710
DOI
:10.4103/0972-124X.124470
PMID
:24554877
Evidence indicates that chronic infections and inflammation are associated with increased risk of cancer development. There has also been considerable evidence that proves the interrelationship between bacterial and viral infections and carcinogenesis. Periodontitis is a chronic oral infection thought to be caused by gram-negative anaerobic bacteria in the dental biofilm. Periodontal bacteria and viruses may act synergistically to cause periodontitis. Many studies have shown that periodontal pockets may act as reservoirs for human papilloma virus, cytomegalovirus, Epstein Barr virus, and suspected agents associated with oral cancer. Periodontitis, characterized by epithelial proliferation and migration, results in a chronic release of inflammatory cytokines, chemokines, growth factors, prostaglandins, and enzymes, all of which are associated with cancer development. This review article intends to shed light on the association between periodontal health and carcinogenesis.
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2
ORIGINAL ARTICLES
Treatment of localized gingival recession using the free rotated papilla autograft combined with coronally advanced flap by conventional (macrosurgery) and surgery under magnification (microsurgical) technique: A comparative clinical study
Suraj Pandey, DS Mehta
November-December 2013, 17(6):765-770
DOI
:10.4103/0972-124X.124500
PMID
:24554888
Background:
The aim of the present study was to evaluate and compare the conventional (macro-surgical) and microsurgical approach in performing the free rotated papilla autograft combined with coronally advanced flap surgery in treatment of localized gingival recession.
Materials and Methods:
A total of 20 sites from 10 systemically healthy patients were selected for the study. The selected sites were randomly divided into experimental site A and experimental site B by using the spilt mouth design. Conventional (macro-surgical) approach for site A and micro-surgery for site B was applied in performing the free rotated papilla autograft combined with coronally advanced flap. Recession depth (RD), recession width (RW) clinical attachment level (CAL.) and width of keratinized tissue (WKT.) were recorded at baseline, 3 months and 6 months post-operatively.
Results:
Both (macro- and microsurgery) groups showed significant clinical improvement in all the parameters (RD, RW, CAL and WKT). However, on comparing both the groups, these parameters did not reach statistical significance.
Conclusion:
Both the surgical procedures were equally effective in treatment of localized gingival recession by the free rotated papilla autograft technique combined with coronally advanced flap. However, surgery under magnification (microsurgery) may be clinically better than conventional surgery in terms of less post-operative pain and discomfort experienced by patients at the microsurgical site.
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3
REVIEW ARTICLES
Redefining the role of dendritic cells in periodontics
Gomathinayagam Venkatesan, Ashita Uppoor, Dilip G Naik
November-December 2013, 17(6):700-705
DOI
:10.4103/0972-124X.124467
PMID
:24554876
A properly functioning adaptive immune system signifies the best features of life. It is diverse beyond compare, tolerant without fail, and capable of behaving appropriately with a myriad of infections and other challenges. Dendritic cells (DCs) are required to explain how this remarkable system is energized and directed. DCs consist of a family of antigen presenting cells, which are bone-marrow-derived cells that patrol all tissues of the body with the possible exceptions of the brain and testes. DCs function to capture bacteria and other pathogens for processing and presentation to T cells in the secondary lymphoid organs. They serve as an essential link between innate and adaptive immune systems and induce both primary and secondary immune responses. As a result of progress worldwide, there is now evidence of a central role for dendritic cells in initiating antigen-specific immunity and tolerance. This review addresses the origins and migration of DCs to target sites, their basic biology and plasticity in playing a key role in periodontal diseases, and finally, selected strategies being pursued to harness its ability to prevent periodontal diseases.
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3
CASE REPORTS
Papillon-lefevre syndrome: Case series and review of literature
Margi V Bhavsar, Nilam A Brahmbhatt, Vishal N Sahayata, Neeta V Bhavsar
November-December 2013, 17(6):806-811
DOI
:10.4103/0972-124X.124530
PMID
:24554896
Papillon-lefevre syndrome (PLS) belongs to a heterogeneous group of skin diseases that are characterized by hyperkeratosis of palms and soles. It is a type IV palmoplantar keratosis (PPK) while the palmoplantar keratodermas share some features of PPK, they are etiologically heterogeneous. PLS differs from other types of PPK by the presence of severe and early onset periodontitis. Genetic studies have shown that mutation in the major gene locus of chromosome 11q14 with the loss of function of cathepsin-C (CTSC) gene is responsible for PLS. CTSC gene mutations are causative for PLS. The resultant loss of CTSC function is responsible for the severe periodontal destruction seen clinically. This report represents two siblings with classical signs and symptoms of PLS.
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4
ORIGINAL ARTICLES
Rotary instruments in the treatment of chronic periodontitis: A randomized clinical trial
Parveen Dahiya, Reet Kamal
November-December 2013, 17(6):748-752
DOI
:10.4103/0972-124X.124493
PMID
:24554884
Background:
The study aimed at comparing the effectiveness of rotary instruments with hand instruments in non-surgical treatment of chronic periodontitis.
Materials and Methods:
Thirty-eight patients with chronic periodontitis, enrolled to this randomized, controlled clinical trial, were divided into two groups. Patients in the control group received scaling and root planing with hand instruments, whereas patients in the test group received treatment with rotary instruments. Clinical assessment by plaque index, bleeding on probing, probing depth, gingival recession, and clinical attachment level was made prior to and at 6 months after treatment. Differences in the clinical parameters were analyzed using the Wilcoxon signed rank test and Mann-Whitney U test.
Results:
Both treatments resulted in a significant improvement in all clinical recordings, but no differences in any of the investigated parameters were observed at baseline between the two groups.
Conclusion:
Non-surgical periodontal therapy with the tested rotary instruments may lead to clinical improvements comparable to those obtained with conventional hand instruments.
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4
3D finite element analysis of immediate loading of single wide versus double implants for replacing mandibular molar
Shrikar R Desai, I Karthikeyan, Reetika Gaddale
November-December 2013, 17(6):777-783
DOI
:10.4103/0972-124X.124504
PMID
:24554890
Purpose:
The purpose of this finite element study was to compare the stresses, strains, and displacements of double versus single implant in immediate loading for replacing mandibular molar.
Materials and Methods:
Two 3D FEM (finite element method) models were made to simulate implant designs. The first model used 5-mm-wide diameter implant to support a single molar crown. The second model used 3.75-3.75 double implant design. Anisotropic properties were assigned to bone model. Each model was analyzed with single force magnitude (100 N) in vertical axis.
Results:
This FEM study suggested that micromotion can be controlled better for double implants compared to single wide-diameter implants. The Von Mises stress for double implant showed 74.44% stress reduction compared to that of 5-mm implant. The Von Mises elastic strain was reduced by 61% for double implant compared to 5-mm implant.
Conclusion:
Within the limitations of the study, when the mesiodistal space for artificial tooth is more than 12.5 mm, under immediate loading, the double implant support should be considered.
[ABSTRACT]
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Assessment of peripheral neutrophil functions in patients with localized aggressive periodontitis in the Indian population
Rahul S Bhansali, RK Yeltiwar, KG Bhat
November-December 2013, 17(6):731-736
DOI
:10.4103/0972-124X.124485
PMID
:24554881
Background:
Localized aggressive periodontitis (LAP) patients exhibit abnormal neutrophil functions to a variety of environmental and host stimuli. The aim of the present study was to evaluate neutrophils chemotaxis, phagocytosis, microbicidal activity and superoxide generation in LAP patients of Indian origin.
Materials and Methods:
Eleven LAP patients and nine healthy subjects were included in the study. Neutrophil chemotaxis was evaluated against an alkali-soluble casein solution using Wilkinson's method. Phagocytosis and microbicidal activity assay were performed using
Candida albicans
as an indicator organism. Nitrobluetetrazolium (NBT) test was used to assess superoxide generation by neutrophils using
E. coli
endotoxin.
Results:
The chemotactic activity and phagocytic and microbicidal activity were observed to be significantly reduced (
P
< 0.01) in LAP neutrophils. On the contrary, superoxide generation was observed to be significantly increased (
P
< 0.01) in LAP neutrophils compared with healthy individuals.
Conclusion:
The results of the present study suggest that neutrophil functions, namely chemotaxis, phagocytosis and microbicidal activity, are deficient LAP patients. However, superoxide generation was significantly increased when stimulated by endotoxins, which may explain the tissue damage seen in LAP. These abnormal neutrophil functions may predispose to increased susceptibility for LAP. Further large-scale studies are required in the Indian population to ascertain the cause-and-effect relationship of defective host factors and aggressive periodontitis and to develop treatment strategies for more predictable periodontal treatment outcome.
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3,196
407
2
The dynamic relationship between pathological migrating teeth and periodontal disease
Surekha R Rathod, Abhay P Kolte, Snehal Chintawar
November-December 2013, 17(6):762-764
DOI
:10.4103/0972-124X.124498
PMID
:24554887
Background:
Pathologic migration is defined as change in tooth position resulting from disruption of the forces that maintain teeth in normal position in relation to their arch. The disruption of equilibrium in tooth position may be caused by several etiologic factors. So, the aim of the study was to evaluate the pathologic tooth migration (PTM) in the upper anterior sextant and its relationship with predisposing and external factors such as bone loss, tooth loss, gingival inflammation, age, parafunctions, lingual interposition in the tongue thrust, and oral habits.
Aim:
The aim of the study was to evaluate the PTM in the upper anterior sextant and its relationship with predisposing and external factors such as bone loss, tooth loss, gingival inflammation, age, parafunctions, lingual interposition in the tongue thrust, and oral habits.
Materials and Methods:
The study sample consisted of 100 subjects of both sexes, with age ranging from 19 to 72 years. The probing pocket depth and gingival index were recorded for each patient. Competency of lips was also evaluated as competent or incompetent. Habits such as tongue thrusting, nail biting, and lip sucking were evaluated in relation to pathological migration of the tooth.
Results:
The results showed that no single factor by itself is clearly associated with PTM. As bone loss increases, the association of PTM with additional factors such as tooth loss and gingival inflammation increases.
Conclusion:
Further studies would be of great help to identify under which circumstances PTM is reversible according to the influence of gingival inflammation, malocclusion, and other factors. This information would contribute to a better understanding of some biological implications of the so-called minor tooth movement.
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3,092
509
-
Evaluation of salivary tumor necrosis factor-alpha in patients with the chronic periodontitis: A case-control study
Hojatollah Yousefimanesh, Robati Maryam, Jahangirnezhad Mahmoud, Ghafourian Boroujerdnia Mehri, Taghipour Mohsen
November-December 2013, 17(6):737-740
DOI
:10.4103/0972-124X.124490
PMID
:24554882
Context:
Periodontitis is a chronic infectious disease that leads to inflammation of the tissues supporting the teeth, bone loss, attachment loss progressively. In chronic periodontitis for starting the host response and inflammatory reaction, the presence of the infectious agent is necessary.
Aims:
One of inflammatory factors is tumor necrosis factor-alpha (TNF-α) that appear to be important in the destruction of periodontal tissues that were examined in this study.
Materials and Methods:
This study was performed in the laboratory and case-control study. The samples of study collected from 30 individuals with chronic periodontitis and 30 healthy controls that matched for age and sex, together. Unstimulated saliva samples were collected from patients and then TNF-α level were measured by enzyme-linked immunosorbent assay and were compared with the control group.
Statistical Analysis Used:
In this study for statistical analysis, Mann-Whitney was used.
Results:
There were differences in mean salivary concentrations of TNF-α in controls and patients. The average concentration in the case group was 9.1 (pg/ml) and the control group was 8.7 (pg/ml), but there was no significant difference between case and control groups (
P
> 0.05).
Conclusions:
The results of this analysis showed no significant relationship between two groups TNF-α concentration.This biomarker can not seem to be a good index to evaluate or predict periodontal disease.
[ABSTRACT]
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[CITATIONS]
[PubMed]
3,052
313
2
CASE REPORTS
Non-familial cherubism: A case report with its surgical management
Shital A Hungund, Vatsala Singh, Chaitra Nagaraja
November-December 2013, 17(6):816-818
DOI
:10.4103/0972-124X.124532
PMID
:24554898
Cherubism is an autosomal-dominant inherited syndrome; it starts in early childhood and involutes by puberty. It is characterized by excessive bone degradation of the jaws and development of fibrous tissue masses. Non-familial cherubism is a rare entity, which needs to be documented. This paper describes the findings of non-familial cherubism. An 11-year-old male patient reported with bilateral swellings of the jaws and unerupted teeth. Extensive gingival overgrowth, cherubic facial appearance, multilocular osteolytic lesions in radiographs and family history lead to the diagnosis of non-familial cherubism. Treatment included full mouth excision of the gingival tissue by gingivectomy with both manual instrumentation and electrosurgery. Patient is being monitored and recalled for frequent follow-ups. Dental practitioners need to be alert with patients presenting with gingival overgrowth.
[ABSTRACT]
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3,031
249
3
ORIGINAL ARTICLES
Prevelance of periodontopathogenic bacteria in subgingival biofilm and atherosclerotic plaques of patients undergoing coronary revascularization surgery
Jaideep Mahendra, Little Mahendra, John Felix, Georgios Romanos
November-December 2013, 17(6):719-724
DOI
:10.4103/0972-124X.124476
PMID
:24554879
Aim:
The objective of the present study was to detect the presence of specific periodontopathogenic bacteria in the coronary plaque of patients with coronary artery disease and to find out the significant association between the periodontal status and the presence of pathogenic bacteria in the coronary plaque.
Materials and Methods:
The study population consisted of 51 patients with chronic generalized periodontitis undergoing coronary artery bypass grafting. Periodontal parameters were recorded and deoxyribonucleic acid was extracted from the subgingival plaque and coronary atherosclerotic plaque samples of the same patients. Polymerase chain reaction was used to amplify the part of 16S ribosomal ribonucleic acid (rRNA) gene to detect the presence of
Aggregatibacter actinomycetemcomitans
(
Aa
)
, Tannerella forsythia
(
Tf
)
, Porphyromonas gingivali
(
Pg
)
, Porphyromonas gingivalis
(
fimA
) gene
and Treponema denticola
(
Td
).
Results:
Aa, Tf, Pg, Pg (fimA)
gene and
Td
were detected in 0%, 31.4%, 45.1% 39.2% and 51% of atherosclerotic plaque samples, respectively.
Tf
was detected in 19.6%,
Pg
in 39.2%,
Pg (fimA)
gene in 33.3% and
Td
in 35.3% of both, subgingival plaque and atherosclerotic plaque samples. Periodontal parameters correlated with the presence of bacteria in coronary plaque.
Aa
could not be detected in coronary plaque samples.
Conclusions:
The study confirmed the detection of Red complex bacteria in coronary plaque samples and these bacteria correlated with the severity of periodontal destruction.
[ABSTRACT]
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[CITATIONS]
[PubMed]
2,854
284
8
CASE REPORTS
Treating congenitally missing teeth with an interdisciplinary approach
Ashutosh Nirola, Shallu J Bhardwaj, Anuj Wangoo, Amardeep Singh Chugh
November-December 2013, 17(6):793-795
DOI
:10.4103/0972-124X.124515
PMID
:24554893
Congenitally missing teeth are frequently presented to the dentist. Interdisciplinary approach may be needed for the proper treatment plan. The available treatment modalities to replace congenitally missing teeth include prosthodontic fixed and removable prostheses, resin bonded retainers, orthodontic movement of maxillary canine to the lateral incisor site and single tooth implants. Dental implants offer a promising treatment option for placement of congenitally missing teeth. Interdisciplinary approach may be needed in these cases. This article aims to present a case report of replacement of bilaterally congenitally missing maxillary lateral incisors and right mandibular second premolar with dental implants.
[ABSTRACT]
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2,233
271
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SECRETARY’S MESSAGE
Second innings!!!!
Balaji Manohar
November-December 2013, 17(6):699-699
DOI
:10.4103/0972-124X.124462
PMID
:24554875
[FULL TEXT]
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[PubMed]
2,014
157
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EDITORIAL
An invigorated second term!
Ashish Sham Nichani
November-December 2013, 17(6):697-697
DOI
:10.4103/0972-124X.124457
PMID
:24554874
[FULL TEXT]
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[EPub]
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1,745
199
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NEWS AND EVENTS
Report of the 38
th
ISP National Conference Periospandanam
Siby T Chennankara, Siby T Chennankara
November-December 2013, 17(6):835-838
DOI
:10.4103/0972-124X.124535
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1,693
121
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PRESIDENT’S MESSAGE
Time to merge boundaries
Ashish Jain
November-December 2013, 17(6):698-698
DOI
:10.4103/0972-124X.124458
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1,623
120
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AUTHOR INDEX, 2013
Author Index, 2013
November-December 2013, 17(6):826-831
Full text not available
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1,649
51
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TITLE INDEX, 2013
Title Index, 2013
November-December 2013, 17(6):832-834
Full text not available
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694
57
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© 2008 Journal of Indian Society of Periodontology | Published by Wolters Kluwer -
Medknow
Online since 1
st
November, 2008