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  Indian J Med Microbiol
 

Figure 6: Immunomicrobial pathogenesis model. (Reprinted from Hajishengallis[30] With copyright permission from Elsevier.) MΦ – Macrophage; DC – Dendritic cell; TNF - Tumor necrosis factor; IL-1 β – Interleukin-1 β; IL-17 – Interleukin-17; CXC chemokine–Cysteine-X-Cysteine chemokine; Th-1 – T helper-1; Th-17 - T helper-17; ROS – Reactive oxygen species; MMP – Matrix metalloproteinases; RANKL - Receptor activator of nuclear factor kappa beta ligand; OPG – Osteoprotegerin; IL-10 – Interleukin-10; B – Bursa of Fabricius cell; T reg – T Regulatory cells; IFN γ – Interferon γ; IL-4 – Interleukin 4; IL-13 – Interleukin-13; OCP – Osteoclast precursor; OCL – Osteoclast; T cell – Thymus derived cell

Figure 6: Immunomicrobial pathogenesis model. (Reprinted from Hajishengallis<sup>[30]</sup> With copyright permission from Elsevier.) MΦ – Macrophage; DC – Dendritic cell; TNF - Tumor necrosis factor; IL-1 β – Interleukin-1 β; IL-17 – Interleukin-17; CXC chemokine–Cysteine-X-Cysteine chemokine; Th-1 – T helper-1; Th-17 - T helper-17; ROS – Reactive oxygen species; MMP – Matrix metalloproteinases; RANKL - Receptor activator of nuclear factor kappa beta ligand; OPG – Osteoprotegerin; IL-10 – Interleukin-10; B – Bursa of Fabricius cell; T reg – T Regulatory cells; IFN γ – Interferon γ; IL-4 – Interleukin 4; IL-13 – Interleukin-13; OCP – Osteoclast precursor; OCL – Osteoclast; T cell – Thymus derived cell